產(chǎn)品詳情
簡單介紹：
Anti-HLA-DRB4抗體產(chǎn)品質(zhì)量穩(wěn)定，實驗效果明顯，貨期快，價格優(yōu)惠，歡迎垂詢訂購！我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關(guān)試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-HLA-DRB4抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-HLA-DRB4
Cat. Number:
Anti-HLA-DRB4抗體KL-18041R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
HLA-DRB4 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in Anti-HLA-DRB4抗體antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5. The presence of DRB4 is linked with allelic variants of DRB1, otherwise it is omitted. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9. [provided by RefSeq, Jul 2008]
Also known as:
DR 4; DR beta 4 chain; DR4; DRB1Anti-HLA-DRB4抗體 transplantation antigen; DRB4; DRB4_HUMAN; HLA class II histocompatibility antigen; HLA class II histocompatibility antigen DR beta 4 chain; HLA-DRB4; Human leucocyte antigen DRB4; Leukocyte antigen; Major histocompatibility complex class II DR beta 4; MHC class II antigen DRB4; MHC class II antigen HLA DR beta; MHC class2 antigen; MHC HLA DR-beta chain.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Dog, Sheep, .
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Immunogen: KLH conjugated synthetic peptide derived from human HLA-DRB4.
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Predicted Molecular Weight: 27kDa.Anti-HLA-DRB4抗體
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-HLA-DRB4抗體
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-HLA-DRB4抗體
Optimal working dilutions must be determined by the end user.
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