產品詳情
簡單介紹：
Anti-FGD3抗體產品質量穩定，實驗效果明顯，貨期快，價格優惠，歡迎垂詢訂購！我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-FGD3抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-FGD3
Cat. Number:
Anti-FGD3抗體KL-16079R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
FGD1 gene mutations result in faciogenital dysplasia (FGDY, Aarskog-Scott syndrome), an X-linked developmental disorder that adversely affects the formation of multiple skeletal structures. FGD1 maps to human chromosome Xp11.21 Anti-FGD3抗體and shares a high degree of sequence identity with the FGD2 (6p21.2) and the FGD3 (9q22.31) proteins. FGD1 encodes a guanine nucleotide exchange factor that specifically activates the Rho GTPase Cdc42. FGD2 is present in several diverse tissues during embryogenesis, suggesting a role in embryonic development. FGD3 stimulates fibroblasts to form filopodia, which are Actin microspikes formed upon the stimulation of Cdc42. All FGD family members contain equivalent signaling domains and a conserved structural organization, which strongly suggests that these signaling domains form a canonical core structure for members of the FGD family of RhoGEF proteins. These proteins control essential signals required during embryonic development.
Also known as:
Faciogenital dysplasia 3; FGD1 family, Anti-FGD3抗體member 3; FGD3; FGD3_HUMAN; FYVE; FYVE, RhoGEF and PH domain containing 3; FYVE, RhoGEF and PH domain containing protein 3; RhoGEF and PH domain-containing protein 3; ZFYVE5; Zinc finger FYVE domain containing protein 5; Zinc finger FYVE domain-containing protein 5.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, .Anti-FGD3抗體
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Immunogen: KLH conjugated synthetic peptide derived from human FGD3.
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Predicted Molecular Weight: 79kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-FGD3抗體
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-FGD3抗體
Optimal working dilutions must be determined by the end user.
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