產品詳情
簡單介紹：
Anti-Fukutin抗體產品質量穩(wěn)定，實驗效果明顯，貨期快，價格優(yōu)惠，歡迎垂詢訂購！我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-Fukutin抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-Fukutin
Cat. Number:
Anti-Fukutin抗體KL-13226R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Fukutin, a secreted protein, is expressed in various tissues in normal individuals. Fukutin colocalizes with a Golgi marker and a granular cytoplasmic distribution, suggesting that fukutin passes through the Golgi before being packagedAnti-Fukutin抗體 into secretory vesicles. Fukutin may be located in the extracellular matrix, where it interacts with and reinforces a large complex encompassing the outside and inside of muscle membranes; alternatively, as a secreted protein, fukutin may cause muscular dystrophy by an unknown mechanism. The fukutin gene is expressed at similar levels in control fetal and ***** brain, but is much reduced in Fukuyama congenital muscular dystrophy (FCMD) brains. Fukutin deficiency affects the modification of glycosylation of DAG1 (α-dystroglycan), which then cannot localize or function properly and may be degraded or eluted from the extracellular surface membrane of the muscle fiber. FCMD is the first human disease known to be caused by an ancient retrotransposal integration. The gene which encodes fukutin maps to human chromosome 9q31.
Also known as:
C10orf125; Chromosome Anti-Fukutin抗體10 open reading frame 125; FUCM_HUMAN; Fucose mutarotase; FUCU; Protein fucU homolog.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse,Anti-Fukutin抗體 Rat, Dog, Pig, Cow, .
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Immunogen: KLH conjugated synthetic peptide derived from human Fukutin.
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Predicted Molecular Weight: 17kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-Fukutin抗體
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-Fukutin抗體
Optimal working dilutions must be determined by the end user.
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