產(chǎn)品詳情
簡單介紹：
Anti-Ep300抗體產(chǎn)品質(zhì)量穩(wěn)定，實驗效果明顯，貨期快，價格優(yōu)惠，歡迎垂詢訂購！我公司長期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關(guān)試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-Ep300抗體用于**組化實驗,WB實驗,相應(yīng)的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-Ep300
Cat. Number:
Anti-Ep300抗體KL-6954R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Cyclic AMP-regulated gene expression frequently involves a DNA element designated the cAMP-regulated enhancer (CRE). Many transcription factors bind to this element, including the protein CREB which is activated asAnti-Ep300抗體 a result of phosphorylation by protein kinase A. It has been shown that protein kinase A-mediated CREB phosphorylation results in its binding to a nuclear protein designated CBP (for CREB-binding protein). These findings suggest that CBP has many of the properties expected of a CREB co-activator. Another high molecular weight transcriptional adapter protein, designated p300, is characterized by three cysteine- and histidine-rich regions, of which the most carboxy terminal region specifically binds the adenovirus E1A protein. p300 molecules lacking an intact E1A binding site bypass E1A repression even in the presence of high concentrations of E1A. Sequence analysis of CBP and p300 has revealed substantial homology, arguing that these proteins are members of a conserved family of co-activators.
Also known as:
CREBBP/EP300 inhibitory protein 1;Anti-Ep300抗體 Cyclic AMP responsive enhancer binding protein; E1A associated protein p300; E1A binding protein p300; E1A-associated protein p300; EC 2.3.1.48; EP300; EP300: E1A binding protein p300; EP300_HUMAN; istone acetyltransferase p300; 300 HAT; RB and P300 binding protein EID 1; Retinoblastoma protein associated protein; RSTS2.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Anti-Ep300抗體Dog, Pig, Cow, Horse, Sheep, .
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Immunogen: KLH conjugated synthetic peptide derived from human KAT3B/p3.
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Predicted Molecular Weight: 264kDa.
Storage:
Shipped at 4℃, Store at -20℃Anti-Ep300抗體 (Avoid repeated freeze/thaw cycles).
Application:
ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-Ep300抗體
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-Ep300抗體
Optimal working dilutions must be determined by the end user.
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