產品詳情
簡單介紹：
Anti-COP1抗體產品質量穩(wěn)定，實驗效果明顯，貨期快，價格優(yōu)惠，歡迎垂詢訂購！我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-COP1抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-COP1
Cat. Number:
Anti-COP1抗體KL-13925R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
COP1 is an E3 ubiquitin ligase protein that mediates ubiquitination and degradation of target proteins such as c-Jun and p53. It is a component of the DCX DET1-COP1 ubiquitin ligase complex which consists of RBX1, Anti-COP1抗體DET1, DDB1, CUL4A and COP1. Localizing to the cytoplasm and to the nucleus, COP1 is primarily expressed in testis, placenta, heart and skeletal muscle. COP1 is a potent inhibitor of p53-dependent transcription and apoptosis but, when phosphorylated by Atm (ataxia telangiectasia mutated) in response to DNA damage, the COP1-p53 complex is disrupted and p53 is allowed to exert its pro-apoptotic properties. In ovarian and breast cancers, COP1 is overexpressed, suggesting a role for COP1 in tumorigenesis.
Also known as:
Constitutive photomorphogenesis Anti-COP1抗體protein 1 homolog; COP; E3 ubiquitin-protein ligase RFWD2; hCOP1; RFWD2; RFWD2_HUMAN; RNF200; ring finger and WD repeat domain 2; RING finger and WD repeat domain protein 2; RING finger protein 200.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep, .
●
Immunogen: KLH conjugated synthetic peptide derived from human COP1.
●
Predicted Molecular Weight: 80kDa.
Storage:
Shipped at 4℃, Store at -20℃ Anti-COP1抗體(Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions mustAnti-COP1抗體 be determined by the end user.
Not yet tested in other applications.
Optimal working dilutions mustAnti-COP1抗體 be determined by the end user.
kl160Bo01 α2-纖溶酶抑制因子(α2PI)多克隆抗體 Polyclonal Antibody to Alpha-2-Plasmin Inhibitor (a2PI)
kl160Hu01 α2-纖溶酶抑制因子(α2PI)多克隆抗體 Polyclonal Antibody to Alpha-2-Plasmin Inhibitor (a2PI)
kl160Mu01 α2-纖溶酶抑制因子(α2PI)多克隆抗體 Polyclonal Antibody to Alpha-2-Plasmin Inhibitor (a2PI)
kl160Ra01 α2-纖溶酶抑制因子(α2PI)多克隆抗體 Polyclonal Antibody to Alpha-2-Plasmin Inhibitor (a2PI)
kl160Rb51 α2-纖溶酶抑制因子(α2PI)多克隆抗體 Polyclonal Antibody to Alpha-2-Plasmin Inhibitor (a2PI)
kl162Bo01 嗅素4(OLFM4)多克隆抗體 Polyclonal Antibody to Olfactomedin 4 (OLFM4)
kl162Hu01 嗅素4(OLFM4)多克隆抗體 Polyclonal Antibody to Olfactomedin 4 (OLFM4)
kl162Mu01 嗅素4(OLFM4)多克隆抗體 Polyclonal Antibody to Olfactomedin 4 (OLFM4)
kl164Ga01 泛素(Ub)多克隆抗體 Polyclonal Antibody to Ubiquitin (Ub)
kl164Gu01 泛素(Ub)多克隆抗體 Polyclonal Antibody to Ubiquitin (Ub)
kl165Bo01 胃蛋白酶原A(PGA)多克隆抗體 Polyclonal Antibody to Pepsinogen A (PGA)
kl165Hu01 胃蛋白酶原A(PGA)多克隆抗體 Polyclonal Antibody to Pepsinogen A (PGA)
kl165Ra01 胃蛋白酶原A(PGA)多克隆抗體 Polyclonal Antibody to Pepsinogen A (PGA)
kl166Ga01 胃蛋白酶原C(PGC)多克隆抗體 Polyclonal Antibody to Pepsinogen C (PGC)
kl166Hu01 胃蛋白酶原C(PGC)多克隆抗體 Polyclonal Antibody to Pepsinogen C (PGC)
kl166Mu01 胃蛋白酶原C(PGC)多克隆抗體 Polyclonal Antibody to Pepsinogen C (PGC)
kl166Ra01 胃蛋白酶原C(PGC)多克隆抗體 Polyclonal Antibody to Pepsinogen C (PGC)
kl167Hu01 前列腺素E合酶(PTGES)多克隆抗體 Polyclonal Antibody to Prostaglandin E Synthase, Microsomal (PTGES)
kl168Hu01 前列腺酸性磷酸酶(ACP3)多克隆抗體 Polyclonal Antibody to Acid Phosphatase 3, Prostatic (ACP3)
kl171Hu01 安眠蛋白1α(MEP1α)多克隆抗體 Polyclonal Antibody to Meprin A Alpha (MEP1a)
kl172Bo01 血小板因子4(PF4)多克隆抗體 Polyclonal Antibody to Platelet Factor 4 (PF4)
