產(chǎn)品詳情
簡單介紹：
Anti-Phospho-CHK2 (Ser33 + Ser35)抗體產(chǎn)品質量穩(wěn)定，實驗效果明顯，貨期快，價格優(yōu)惠，歡迎垂詢訂購！我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-Phospho-CHK2 (Ser33 + Ser35)抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-Phospho-CHK2 (Ser33 + Ser35)
Cat. Number:
Anti-Phospho-CHK2 (Ser33 + Ser35)抗體KL-13908R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead-associated protein interaction domain essential forAnti-Phospho-CHK2 (Ser33 + Ser35)抗體 activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated, the encoded protein is known to inhibit CDC25C phosphatase, preventing entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1. In addition, this protein interacts with and phosphorylates BRCA1, allowing BRCA1 to restore survival after DNA damage. Mutations in this gene have been linked with Li-Fraumeni syndrome, a highly penetrant familial cancer phenotype usually associated with inherited mutations in TP53. Also, mutations in this gene are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors. This nuclear protein is a member of the CDS1 subfamily of serine/threonine protein kinases. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Also known as:
Chk2 (phospho S33 + S35); p-Chk2Anti-Phospho-CHK2 (Ser33 + Ser35)抗體 (phospho S33 + S35); bA444G7; CHK2 checkpoint homolog; CHK2_HUMAN; Serine/threonine-protein kinase Chk2; CDS 1; CDS1; Checkpoint kinase 2; Checkpoint like protein CHK2; Chek 2; Chek2; Chk 2; CHK2 checkpoint homolog (S. pombe); CHK2 checkpoint homolog; HuCds 1; HuCds1; LFS 2; LFS2; PP1425; RAD 53; RAD53; Rad53 homolog; Serine/threonine protein kinase Chk2.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, .
●
Immunogen: KLH conjugated Synthesised phosphopeptide derived from human.
●
Predicted Molecular Weight: 61kDa.Anti-Phospho-CHK2 (Ser33 + Ser35)抗體
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be Anti-Phospho-CHK2 (Ser33 + Ser35)抗體determined by the end user.
Not yet tested in other applications.
Optimal working dilutions must be Anti-Phospho-CHK2 (Ser33 + Ser35)抗體determined by the end user.
kl044Ga01 生長**(GH)多克隆抗體 Polyclonal Antibody to Growth Hormone (GH)
kl266Hu01 胰高血糖素(GC)多克隆抗體 Polyclonal Antibody to Glucagon (GC)
kl266Mu01 胰高血糖素(GC)多克隆抗體 Polyclonal Antibody to Glucagon (GC)
kl266Ra01 胰高血糖素(GC)多克隆抗體 Polyclonal Antibody to Glucagon (GC)
kl438Hu01 促生長**釋放**(GHRH)多克隆抗體 Polyclonal Antibody to Growth Hormone Releasing Hormone (GHRH)
kl438Mu01 促生長**釋放**(GHRH)多克隆抗體 Polyclonal Antibody to Growth Hormone Releasing Hormone (GHRH)
kl438Ra01 促生長**釋放**(GHRH)多克隆抗體 Polyclonal Antibody to Growth Hormone Releasing Hormone (GHRH)
kl438Po01 促生長**釋放**(GHRH)多克隆抗體 Polyclonal Antibody to Growth Hormone Releasing Hormone (GHRH)
kl438Bo01 促生長**釋放**(GHRH)多克隆抗體 Polyclonal Antibody to Growth Hormone Releasing Hormone (GHRH)
kl438Cp01 促生長**釋放**(GHRH)多克隆抗體 Polyclonal Antibody to Growth Hormone Releasing Hormone (GHRH)
kl409An01 血紅蛋白(HB)多克隆抗體 Polyclonal Antibody to Hemoglobin (HB)
kl409Ha01 血紅蛋白(HB)多克隆抗體 Polyclonal Antibody to Hemoglobin (HB)
kl737Ge01 吲哚乙酸(IAA)多克隆抗體 Polyclonal Antibody to Indole 3 Acetic Acid (IAA)
kl091Hu01 輕肽網(wǎng)格蛋白B(CLTB)多克隆抗體 Polyclonal Antibody to Clathrin, Light Polypeptide B (CLTB)
kl091Mu01 輕肽網(wǎng)格蛋白B(CLTB)多克隆抗體 Polyclonal Antibody to Clathrin, Light Polypeptide B (CLTB)
kl091Ra01 輕肽網(wǎng)格蛋白B(CLTB)多克隆抗體 Polyclonal Antibody to Clathrin, Light Polypeptide B (CLTB)
kl462Ge01 皮質醇(Cor)多克隆抗體 Polyclonal Antibody to Cortisol (Cor)
kl049Gu01 干擾素γ(IFNγ)多克隆抗體 Polyclonal Antibody to Interferon Gamma (IFNg)
kl049Rb52 干擾素γ(IFNγ)多克隆抗體 Polyclonal Antibody to Interferon Gamma (IFNg)
kl049Si01 干擾素γ(IFNγ)多克隆抗體 Polyclonal Antibody to Interferon Gamma (IFNg)
kl049Ca01 干擾素γ(IFNγ)多克隆抗體 Polyclonal Antibody to Interferon Gamma (IFNg)
kl049Po01 干擾素γ(IFNγ)多克隆抗體 Polyclonal Antibody to Interferon Gamma (IFNg)
