產品詳情
簡單介紹：
Anti-CENTD1抗體產品質量穩定，實驗效果明顯，貨期快，價格優惠，歡迎垂詢訂購！我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-CENTD1抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-CENTD1
Cat. Number:
Anti-CENTD1抗體KL-13845R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 Anti-CENTD1抗體GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics.The ADP-ribosylation factor (ARF) family of small GTP-binding proteins are involved in vesicular transport regulation and in controlling cytoskeletal organ-ization and cell adhesion. These proteins are best characterized as regulators of membrane traffic. The Centaurin GTPase-activating protein family comprise a subset of ARF regulatory molecules that transduce PI 3-kinase activation into coordinated control of ARF-dependent pathways. This family includes ARAP2, a GTPase-activating protein that controls Actin cytoskeleton remodeling by regulating Rho ARF family members. The ARAP2 protein localizes to the cytoplasm and is expressed in various tissues including brain, thymus, lymph node, thyroid, spinal cord, trachea, heart, skeletal muscle, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes. It contains one ARF-GAP domain, five PH domains, one Ras-associating domain, one Rho-GAP domain and one SAM (sterile a motif) domain.
Also known as:
ARAP2; Arf GAP Rho GAP ankyrinAnti-CENTD1抗體 repeat and pleckstrin homology domain containing protein 2; Centaurin delta 1; Cnt d1; FLJ13675; KIAA0580; PARX protein.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, .
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Immunogen: KLH conjugated synthetic peptide derived from human CENTD1.
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Predicted Molecular Weight: 193kDa.
Storage:
Shipped at 4℃, Store at -20℃Anti-CENTD1抗體 (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000Anti-CENTD1抗體 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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