產(chǎn)品詳情
簡單介紹：
Anti-PVRL1抗體產(chǎn)品質(zhì)量穩(wěn)定，實驗效果明顯，貨期快，價格優(yōu)惠，歡迎垂詢訂購！我公司長期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關(guān)試劑、熒光標(biāo)記抗體、單克隆抗體、多克隆抗體、各種標(biāo)記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-PVRL1抗體用于**組化實驗,WB實驗,相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,FITC標(biāo)記,BIO等。
詳情介紹：
Rabbit Anti-PVRL1
Cat. Number:
Anti-PVRL1抗體KL-11126R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Nectin is a Ca2+-independent homophilic cell adhesion molecule that belongs to the immunoglobulin superfamily. Human Nectin is identical to the poliovirus receptor-related protein (PRR) and is identified to be the alphaherpesvirus entry mediator. Nectin constitutes a family consisting of at least nectin 1, 2 and 3. Nectin Anti-PVRL1抗體2 and 3 are ubiquitously expressed, whereas nectin 1 is abundantly expressed in the brain. Nectin 1 exists as nectin 1? and 1∫/HIgR, produced by alternative splicing. The cytoplasmic regions of Nectin 1?, but not Nectin 1∫/HIgR, have a C-terminal conserved motif (E/A-X-Y-V). This motif interacts with the PDZ domain of the F-Actin-binding protein, afadin, through which it is linked to the Actin cytoskeleton. Nectin 1, also designated HveC/ PRR1, allows the entry of herpes simplex virus type 1 (HSV-1) and HSV-2 into mammalian cells. The interaction of virus envelope glycoprotein D (gD) with nectin 1 is an essential step in the process leading to membrane fusion; the gD binding site is located at the first Ig-like domain of Nectin 1. Both the transinteraction of nectin and the interaction of nectin with afadin are necessary for their co-localization with E-cadherin and catenins at adherens junctions.
Also known as:
CD111; CD111 antigen; Anti-PVRL1抗體CLPED1; ectodermal dysplasia 4 (Margarita Island type); ED4; Herpes virus entry mediator C; Herpesvirus entry mediator C; Herpesvirus Ig like receptor; Herpesvirus Ig-like receptor; HIgR; HveC; Nectin 1; Nectin-1; Nectin1; OFC7; OROFACIAL CLEFT 7; Poliovirus receptor related protein 1; poliovirus receptor-like 1; Poliovirus receptor-related protein 1; PRR; PRR1; PVRL 1; PVRL1; PVRL1_HUMAN; PVRR; PVRR1; SK-12.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Dog, Cow, Rabbit, .
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Immunogen: KLH conjugated synthetic peptide derived from human PVRL1/CD111/Nectin1.
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Predicted Molecular Weight: 54kDa.
Storage:
Shipped at 4℃, Store Anti-PVRL1抗體at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working Anti-PVRL1抗體dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working Anti-PVRL1抗體dilutions must be determined by the end user.
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