產品詳情
簡單介紹：
Anti-CDKN2A/p14ARF抗體產品質量穩定，實驗效果明顯，貨期快，價格優惠，歡迎垂詢訂購！我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-CDKN2A/p14ARF抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-CDKN2A/p14ARF
Cat. Number:
Anti-CDKN2A/p14ARF抗體KL-1174R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene generates several transcript variants which differ in their first exons. At least three alternatively splicedAnti-CDKN2A/p14ARF抗體 variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants. This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, MDM1, a protein responsible for the degradation of p53. In spite of the structural and functional differences, the CDK inhibitor isoforms and the ARF product encoded by this gene, through the regulatory roles of CDK4 and p53 in cell cycle G1 progression, share a common functionality in cell cycle G1 control. This gene is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene. CDKN2A.
Also known as:
CD2A2_HUMAN; p14 Anti-CDKN2A/p14ARF抗體ARF; TP16; p16; CDKN2; MTS1; INK4a; CMM2; MLM; ARF; p16INK4a; INK4; p16-INK4a; p14; p16-INK4; p16INK4A; p16INK4; p19; p19ARF; CDK4I; MTS-1.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Mouse, Rat, .
●
Immunogen: KLH conjugated synthetic peptide derived from human CDKN2A/p14ARF.
●
Predicted Molecular Weight: 19kDa.
Storage:
Shipped at 4℃, Store Anti-CDKN2A/p14ARF抗體at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-200 IF=1:100-500
Not yet tested in other applications.
Optimal working Anti-CDKN2A/p14ARF抗體dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working Anti-CDKN2A/p14ARF抗體dilutions must be determined by the end user.
kl859Hu01 甘露聚糖結合凝集素關聯絲氨酸蛋白酶2(MASP2)多克隆抗體 Polyclonal Antibody to Mannose Associated Serine Protease 2 (MASP2)
kl860Hu01 上皮中性粒細胞激活肽78(ENA78)多克隆抗體 Polyclonal Antibody to Epithelial Neutrophil Activating Peptide 78 (ENA78)
kl860Mu01 上皮中性粒細胞激活肽78(ENA78)多克隆抗體 Polyclonal Antibody to Epithelial Neutrophil Activating Peptide 78 (ENA78)
kl860Ra01 上皮中性粒細胞激活肽78(ENA78)多克隆抗體 Polyclonal Antibody to Epithelial Neutrophil Activating Peptide 78 (ENA78)
kl861Hu01 補體成分3(C3)多克隆抗體 Polyclonal Antibody to Complement Component 3 (C3)
kl861Mu01 補體成分3(C3)多克隆抗體 Polyclonal Antibody to Complement Component 3 (C3)
kl861Po01 補體成分3(C3)多克隆抗體 Polyclonal Antibody to Complement Component 3 (C3)
kl861Ra01 補體成分3(C3)多克隆抗體 Polyclonal Antibody to Complement Component 3 (C3)
kl862Hu01 補體成分2(C2)多克隆抗體 Polyclonal Antibody to Complement Component 2 (C2)
kl866Bo01 甲狀旁腺**(PTH)多克隆抗體 Polyclonal Antibody to klathyroid Hormone (PTH)
kl866Ca01 甲狀旁腺**(PTH)多克隆抗體 Polyclonal Antibody to klathyroid Hormone (PTH)
kl866Ga01 甲狀旁腺**(PTH)多克隆抗體 Polyclonal Antibody to klathyroid Hormone (PTH)
kl866Hu01 甲狀旁腺**(PTH)多克隆抗體 Polyclonal Antibody to klathyroid Hormone (PTH)
kl866Mu01 甲狀旁腺**(PTH)多克隆抗體 Polyclonal Antibody to klathyroid Hormone (PTH)
kl866Po01 甲狀旁腺**(PTH)多克隆抗體 Polyclonal Antibody to klathyroid Hormone (PTH)
kl866Ra01 甲狀旁腺**(PTH)多克隆抗體 Polyclonal Antibody to klathyroid Hormone (PTH)
kl867Hu01 脂蛋白關聯磷脂酶A2(LpPLA2)多克隆抗體 Polyclonal Antibody to Phospholikle A2, Lipoprotein Associated (LpPLA2)
kl867Mu01 脂蛋白關聯磷脂酶A2(LpPLA2)多克隆抗體 Polyclonal Antibody to Phospholikle A2, Lipoprotein Associated (LpPLA2)
kl867Ra01 脂蛋白關聯磷脂酶A2(LpPLA2)多克隆抗體 Polyclonal Antibody to Phospholikle A2, Lipoprotein Associated (LpPLA2)
kl868Hu01 內皮型一氧化氮合酶(NOS3)多克隆抗體 Polyclonal Antibody to Nitric Oxide Synthase 3, Endothelial (NOS3)
kl868Mu01 內皮型一氧化氮合酶(NOS3)多克隆抗體 Polyclonal Antibody to Nitric Oxide Synthase 3, Endothelial (NOS3)
