產品詳情
簡單介紹：
Anti-phospho-IRS1 (Ser636 + Ser639)抗體產品質量穩定，實驗效果明顯，貨期快，價格優惠，歡迎垂詢訂購！我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-phospho-IRS1 (Ser636 + Ser639)抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-phospho-IRS1 (Ser636 + Ser639)
Cat. Number:
Anti-phospho-IRS1 (Ser636 + Ser639)抗體KL-3201R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Insulin receptor substrates (IRS) are responsible for several insulin related activities, such as glucose homeostasis, cell growth, cell Anti-phospho-IRS1 (Ser636 + Ser639)抗體transformation, apoptosis and insulin signal transduction. Serine/threonine phosphorylation of IRS1 has been demonstrated to be a negative regulator of insulin signaling and is responsible for its degradation, although IRS1 degradation pathways are not well understood. IRS1 has also been shown to be constitutively activated in cancers such as breast cancer, Wilm's tumors, and adrenal cortical carcinomas, thus making IRS1 phosphorylation and subsequent degradation an attractive therapeutic target. To date there have been four subtypes identified: IRS1, 2, 3 and 4, with IRS1 being widely expressed.
Also known as:
IRS1 (phospho S636); p-IRS1 (phospho S636);Anti-phospho-IRS1 (Ser636 + Ser639)抗體 IRS1 (phospho S639); p-IRS1 (phospho S639); IRS-1(Phospho-Ser636); IRS-1(Phospho-Ser639); p-IRS1; IRS1(phospho-Ser636/639); HIRS 1; HIRS1; Insulin Receptor Substrate 1; IRS-1; IRS 1; IRS1; OTTHUMP00000164234; IRS1_HUMAN.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, .
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Immunogen: KLH conjugated synthesised phosphopeptide derived from human.
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Predicted Molecular Weight: 132kDa.Anti-phospho-IRS1 (Ser636 + Ser639)抗體
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-phospho-IRS1 (Ser636 + Ser639)抗體
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-phospho-IRS1 (Ser636 + Ser639)抗體
Optimal working dilutions must be determined by the end user.
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