產(chǎn)品詳情
簡(jiǎn)單介紹：
Anti-HECW1抗體產(chǎn)品質(zhì)量穩(wěn)定，實(shí)驗(yàn)效果明顯，貨期快，價(jià)格優(yōu)惠，歡迎垂詢訂購(gòu)！我公司長(zhǎng)期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗(yàn)所需全部相關(guān)試劑、熒光標(biāo)記抗體、單克隆抗體、多克隆抗體、各種標(biāo)記的二抗IgG/IgM/IgD/IgA等科研實(shí)驗(yàn)抗體。Anti-HECW1抗體用于**組化實(shí)驗(yàn),WB實(shí)驗(yàn),相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,FITC標(biāo)記,BIO等。
詳情介紹：
Rabbit Anti-HECW1
Cat. Number:
Anti-HECW1抗體KL-11692R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
NEDL1 is a 1,606 amino acid cytoplasmic protein predominantly expressed in neurons of ***** and fetal brain. NEDL1 functions as an E3 ubiquitin-protein ligase that, characteristic of E3 ligase proteins, accepts ubiquitin (in the form of a thioester) from an E2 ubiquitin-conjugating enzyme and transfers that ubiquitin residue to Anti-HECW1抗體substrates targeted for degradation. NEDL1 mediates ubiquitination and subsequent degradation of Dvl-1 and targets mutant SOD-1. NEDL1 forms cytotoxic aggregates with Dvl, TRAP-?and mutant SOD1 that lead to motor neuron death in FALS (familial amyotrophic lateral sclerosis). individuals affect by FALS (also known as Lou Gehrig's disease) experience muscle weakness and atrophy throughout the body. FALS is caused by the degeneration of upper and lower motor neurons resulting in loss of signal to muscles.
Also known as:
NEDL1; C2 and WW domain-containingAnti-HECW1抗體 protein 1; E3 ubiquitin-protein ligase HECW1; HECT; HECT type E3 ubiquitin ligase; HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1; HECT, C2 and WW domain-containing protein 1; HECW 1; Hecw1; HECW1_HUMAN; hNEDL1; NEDD4 like ubiquitin protein ligase 1; NEDD4-like E3 ubiquitin-protein ligase 1; NEDL-1; NEDL 1.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Chicken, Anti-HECW1抗體Dog, Cow, .
●
Immunogen: KLH conjugated synthetic peptide derived from human HECW1 (2.
●
Predicted Molecular Weight: 179kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-HECW1抗體
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-HECW1抗體
Optimal working dilutions must be determined by the end user.
kl373Hu01 結(jié)蛋白(Des)多克隆抗體 Polyclonal Antibody to Desmin (Des)
kl373Mu01 結(jié)蛋白(Des)多克隆抗體 Polyclonal Antibody to Desmin (Des)
kl373Ra01 結(jié)蛋白(Des)多克隆抗體 Polyclonal Antibody to Desmin (Des)
kl374Ra01 GATA結(jié)合蛋白4(GATA4)多克隆抗體 Polyclonal Antibody to GATA Binding Protein 4 (GATA4)
kl376Hu01 輔肌動(dòng)蛋白α2(ACTN2)多克隆抗體 Polyclonal Antibody to Actinin Alpha 2 (ACTN2)
kl376Mu01 輔肌動(dòng)蛋白α2(ACTN2)多克隆抗體 Polyclonal Antibody to Actinin Alpha 2 (ACTN2)
kl380Bo01 血管活性腸肽(VIP)多克隆抗體 Polyclonal Antibody to Vasoactive Intestinal Peptide (VIP)
kl380Hu01 血管活性腸肽(VIP)多克隆抗體 Polyclonal Antibody to Vasoactive Intestinal Peptide (VIP)
kl380Mu01 血管活性腸肽(VIP)多克隆抗體 Polyclonal Antibody to Vasoactive Intestinal Peptide (VIP)
kl380Ra01 血管活性腸肽(VIP)多克隆抗體 Polyclonal Antibody to Vasoactive Intestinal Peptide (VIP)
kl382Hu01 蛋白激酶Bγ(PKBγ)多克隆抗體 Polyclonal Antibody to Protein Kinase B Gamma (PKBg)
kl383Hu01 磷酸肌醇-3-激酶2α肽(PI3K2α)多克隆抗體 Polyclonal Antibody to Phosphoinositide-3-Kinase Class-2-Alpha Polypeptide (PIK3C2a)
kl383Mu01 磷酸肌醇-3-激酶2α肽(PI3K2α)多克隆抗體 Polyclonal Antibody to Phosphoinositide-3-Kinase Class-2-Alpha Polypeptide (PIK3C2a)
kl384Hu01 白介素23(IL23)多克隆抗體 Polyclonal Antibody to Interleukin 23 (IL23)
kl384Mu01 白介素23(IL23)多克隆抗體 Polyclonal Antibody to Interleukin 23 (IL23)
kl384Ra01 白介素23(IL23)多克隆抗體 Polyclonal Antibody to Interleukin 23 (IL23)
kl385Hu01 白介素27(IL27)多克隆抗體 Polyclonal Antibody to Interleukin 27 (IL27)
kl385Ra01 白介素27(IL27)多克隆抗體 Polyclonal Antibody to Interleukin 27 (IL27)
kl389Mu01 補(bǔ)體成分4a(C4a)多克隆抗體 Polyclonal Antibody to Complement Component 4a (C4a)
