產品詳情
簡單介紹：
Anti-HMGCR抗體產品質量穩定，實驗效果明顯，貨期快，價格優惠，歡迎垂詢訂購！我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-HMGCR抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-HMGCR
Cat. Number:
Anti-HMGCR抗體KL-5068R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism Anti-HMGCR抗體mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase. Normally in mammalian cells this enzyme is suppressed by cholesterol derived from the internalization and degradation of low density lipoprotein (LDL) via the LDL receptor. Competitive inhibitors of the reductase induce the expression of LDL receptors in the liver, which in turn increases the catabolism of plasma LDL and lowers the plasma concentration of cholesterol, an important determinant of atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Also known as:
3H3M; HMDH_HUMAN; 3 hydroxy 3Anti-HMGCR抗體 methylglutaryl Coenzyme A reductase; 3-hydroxy-3-methylglutaryl-coenzyme A reductase; HMG CoA reductase; HMG CoAR; HMG-CoA reductase; y Hmgcr; Red antibody MGC103269; 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isoform 1.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, .
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Immunogen: KLH conjugated synthetic peptide derived from human HMGCR.
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Predicted Molecular Weight: 97kDa.Anti-HMGCR抗體
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-HMGCR抗體
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-HMGCR抗體
Optimal working dilutions must be determined by the end user.
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