產(chǎn)品詳情
簡(jiǎn)單介紹：
Anti-GCLC抗體產(chǎn)品質(zhì)量穩(wěn)定，實(shí)驗(yàn)效果明顯，貨期快，價(jià)格優(yōu)惠，歡迎垂詢(xún)訂購(gòu)！我公司長(zhǎng)期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗(yàn)所需全部相關(guān)試劑、熒光標(biāo)記抗體、單克隆抗體、多克隆抗體、各種標(biāo)記的二抗IgG/IgM/IgD/IgA等科研實(shí)驗(yàn)抗體。Anti-GCLC抗體用于**組化實(shí)驗(yàn),WB實(shí)驗(yàn),相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,FITC標(biāo)記,BIO等。
詳情介紹：
Rabbit Anti-GCLC
Cat. Number:
Anti-GCLC抗體KL-8402R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The GCLC gene consists of 16 exons and encodes the 636 amino acid protein g-GCSc (g-glutamylcysteine synthetase heavy subunit), also designated g-L-glutamate-L-cysteine ligase catalytic subunit (GLCLC). g-GCSc is expressed in Anti-GCLC抗體hemocytes, brain, liver and kidney. g-GCSc associates with a regulatory or modifier subunit, g-GCSm (g-glutamylcysteine synthetase light subunit), to form a heterodimer, g-GCS. g-GCS is the first enzyme involved and the rate determining step in glutathione biosynthesis. Oxidants, cadium and methyl mercury upregulate the transcription of g-GCS. H2O2 regulation depends on the Yap1 protein and the presence of glutamate, glutamine and lysine. Cadium regulates transcription through proteins Met-4, Met-31 and Met-32. Cbf1, a DNA binding protein, inhibits transcription of g-GCS. Chemopreventive compounds cause increased levels of g-GCSc in kidney tissues, which may protect against chemically induced carcinogenesis. A His370Leu amino acid change in g-GCSc causes deficiencies in activity which are responsible for hemolytic anemia and low red blood cell glutathione levels. Defects in GCLC are the cause of hemolytic anemia.
Also known as:
Gamma ECS; Gamma GCS; Gamma Anti-GCLC抗體glutamylcysteine synthetase; Gamma-ECS; Gamma-glutamylcysteine synthetase; GCL; GCLC; GCLM; GCS; GCS Heavy Chain antibody GLCL; GLCLC; GLCLR; Glutamate cysteine ligase catalytic subunit; Glutamate cysteine ligase (gamma glutamylcysteine synthetase) regulatory (30.8kD); Glutamate cysteine ligase catalytic subunit; Glutamate cysteine ligase modifier subunit; Glutamate cysteine ligase regulatory protein; Glutamate cysteine ligase regulatory subunit; Glutamate--cysteine ligase catalytic subunit; GSH1_HUMAN.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, .
●
Immunogen: KLH conjugated synthetic Anti-GCLC抗體peptide derived from human GCLC.
●
Predicted Molecular Weight: 73kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200
Not yet tested in other applications. Anti-GCLC抗體
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-GCLC抗體
Optimal working dilutions must be determined by the end user.
kl284Ga01 肝素輔因子Ⅱ(HCⅡ)多克隆抗體 Polyclonal Antibody to Heklin Cofactor II (HCII)
kl284Hu01 肝素輔因子Ⅱ(HCⅡ)多克隆抗體 Polyclonal Antibody to Heklin Cofactor II (HCII)
kl284Mu01 肝素輔因子Ⅱ(HCⅡ)多克隆抗體 Polyclonal Antibody to Heklin Cofactor II (HCII)
kl284Ra01 肝素輔因子Ⅱ(HCⅡ)多克隆抗體 Polyclonal Antibody to Heklin Cofactor II (HCII)
kl284Rb51 肝素輔因子Ⅱ(HCⅡ)多克隆抗體 Polyclonal Antibody to Heklin Cofactor II (HCII)
kl292Ga01 α-胞襯蛋白(SPTAN1)多克隆抗體 Polyclonal Antibody to Alpha-Fodrin (SPTAN1)
kl292Hu01 α-胞襯蛋白(SPTAN1)多克隆抗體 Polyclonal Antibody to Alpha-Fodrin (SPTAN1)
kl292Mu01 α-胞襯蛋白(SPTAN1)多克隆抗體 Polyclonal Antibody to Alpha-Fodrin (SPTAN1)
kl292Ra01 α-胞襯蛋白(SPTAN1)多克隆抗體 Polyclonal Antibody to Alpha-Fodrin (SPTAN1)
kl293Bo01 谷氨酸脫氫酶(GDH)多克隆抗體 Polyclonal Antibody to Glutamate Dehydrogenase 1 (GDH)
kl293Hu01 谷氨酸脫氫酶(GDH)多克隆抗體 Polyclonal Antibody to Glutamate Dehydrogenase 1 (GDH)
kl293Mu01 谷氨酸脫氫酶(GDH)多克隆抗體 Polyclonal Antibody to Glutamate Dehydrogenase 1 (GDH)
kl293Ra01 谷氨酸脫氫酶(GDH)多克隆抗體 Polyclonal Antibody to Glutamate Dehydrogenase 1 (GDH)
kl295Bo01 谷胱甘肽過(guò)氧化酶1(GPX1)多克隆抗體 Polyclonal Antibody to Glutathione Peroxidase 1 (GPX1)
kl295Hu01 谷胱甘肽過(guò)氧化酶1(GPX1)多克隆抗體 Polyclonal Antibody to Glutathione Peroxidase 1 (GPX1)
kl295Mu01 谷胱甘肽過(guò)氧化酶1(GPX1)多克隆抗體 Polyclonal Antibody to Glutathione Peroxidase 1 (GPX1)
kl295Po01 谷胱甘肽過(guò)氧化酶1(GPX1)多克隆抗體 Polyclonal Antibody to Glutathione Peroxidase 1 (GPX1)
kl295Ra01 谷胱甘肽過(guò)氧化酶1(GPX1)多克隆抗體 Polyclonal Antibody to Glutathione Peroxidase 1 (GPX1)
