Cat. Number:

Anti-C1orf194抗體KL-15052R

Quantity size:

0.2ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and isAnti-C1orf194抗體 a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf194 gene product has been provisionally designated C1orf194 pending further characterization. There are two isoforms of C1orf194 that are produced as a result of alternative splicing events.

Also known as:

C1orf194; CA194_HUMAN; Anti-C1orf194抗體Chromosome 1 open reading frame 194; Hypothetical protein LOC1270032; OTTHUMP00000013446; OTTHUMP00000013448; Uncharacterized protein C1orf194.

Specificity:

Storage:

Shipped at 4℃, Store Anti-C1orf194抗體at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working Anti-C1orf194抗體dilutions must be determined by the end user.