產(chǎn)品詳情
簡(jiǎn)單介紹：
Anti-phospho-CstF64 (Ser83)抗體產(chǎn)品質(zhì)量穩(wěn)定，實(shí)驗(yàn)效果明顯，貨期快，價(jià)格優(yōu)惠，歡迎垂詢訂購(gòu)！我公司長(zhǎng)期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗(yàn)所需全部相關(guān)試劑、熒光標(biāo)記抗體、單克隆抗體、多克隆抗體、各種標(biāo)記的二抗IgG/IgM/IgD/IgA等科研實(shí)驗(yàn)抗體。Anti-phospho-CstF64 (Ser83)抗體用于**組化實(shí)驗(yàn),WB實(shí)驗(yàn),相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,FITC標(biāo)記,BIO等。
詳情介紹：
Rabbit Anti-phospho-CstF64 (Ser83)
Cat. Number:
Anti-phospho-CstF64 (Ser83)抗體KL-8522R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Polyadenylation of mRNA precursors is a two-step reaction that requires multiple protein factors. The first step, endonucleolytic cleavage of polyadenylation substrates, requires CstF (cleavage stimulation factor), a heterotrimer that is composed of three distinct subunits. CstF-64 contains an RNA binding domain and is responsible for the RNA binding activity of CstF. CstF-64 is expressed in all somatic cells and in pre- andAnti-phospho-CstF64 (Ser83)抗體 postmeiotic, but not meiotic, germ cells. However, a large variant of CstF-64, called t CstF-64, is abundantly expressed in meiotic and postmeiotic cells in the testis and to a lesser extent in the brain, and promotes the germ cell pattern of polyadenylation. The gene encoding CstF-64 (designated CSTF2) maps to the X chromosome, whereas t CstF-64 is encoded by an autosomal gene. The increase in CstF-64 concentration during B cell activation switches IgM heavy chain mRNA expression from membrane-bound to secreted forms, suggesting that CstF-64 plays a key role in regulating IgM heavy chain expression during B cell differentiation.
Also known as:
p-CstF-64 (Ser83); p-CstF-64 (S83); Anti-phospho-CstF64 (Ser83)抗體CstF64 (phospho-Ser83); CstF64 (phospho-S83); CSTF2T; CF1 64 kDa subunit, tau variant; Cleavage stimulation factor 64 kDa subunit, tau variant; CSTF 64 kDa subunit, tau variant; KIAA0689; TauCstF64; CSTF2_HUMAN.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, .
●
Immunogen: KLH conjugated synthesised phosphopeptide derived from human CstF64 around the phosphorylation site of Ser83.
●
Predicted Molecular Weight: 61kDa.
Storage:
Shipped at 4℃, Store at -20℃Anti-phospho-CstF64 (Ser83)抗體 (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200
Not yet tested in other applications.
Optimal working Anti-phospho-CstF64 (Ser83)抗體dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working Anti-phospho-CstF64 (Ser83)抗體dilutions must be determined by the end user.
kl314Ra01 腺瘤息肉病大腸桿菌蛋白(APC)多克隆抗體 Polyclonal Antibody to Adenomatosis Polyposis Coli Protein (APC)
kl389Mu01 心營(yíng)養(yǎng)素樣細(xì)胞因子1(CLCF1)多克隆抗體 Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1)
kl642Hu02 膜突蛋白(MSN)多克隆抗體 Polyclonal Antibody to Moesin (MSN)
kl642Ra01 膜突蛋白(MSN)多克隆抗體 Polyclonal Antibody to Moesin (MSN)
kl746Hu01 外周鞘磷脂蛋白22(PMP22)多克隆抗體 Polyclonal Antibody to Peripheral Myelin Protein 22 (PMP22)
kl099Hu01 低密度脂蛋白受體相關(guān)蛋白8(LRP8)多克隆抗體 Polyclonal Antibody to Low Density Lipoprotein Receptor Related Protein 8 (LRP8)
kl117Hu01 T-細(xì)胞表面糖蛋白CD3ε(CD3ε)多克隆抗體 Polyclonal Antibody to T-Cell Surface Glycoprotein CD3 Epsilon (CD3e)
kl563Hu01 絲裂原激活蛋白激酶激酶3(MAP2K3)多克隆抗體 Polyclonal Antibody to Mitogen Activated Protein Kinase Kinase 3 (MAP2K3)
kl576Hu01 絲裂原激活蛋白激酶9(MAPK9)多克隆抗體 Polyclonal Antibody to Mitogen Activated Protein Kinase 9 (MAPK9)
kl947Hu01 RAR相關(guān)孤兒素受體α(RORα)多克隆抗體 Polyclonal Antibody to RAR Related Orphan Receptor Alpha (RORa)
kl222Hu02 干擾素β(IFNβ)多克隆抗體 Polyclonal Antibody to Interferon Beta (IFNb)
kl835Hu02 促腎上皮質(zhì)**釋放**(CRH)多克隆抗體 Polyclonal Antibody to Corticotropin Releasing Hormone (CRH)
kl343Mu01 Bcl2關(guān)聯(lián)X蛋白(Bax)多克隆抗體 Polyclonal Antibody to Bcl2 Associated X Protein (Bax)
