產(chǎn)品詳情
簡(jiǎn)單介紹：
Anti-phospho-CBL2 (Tyr731)抗體產(chǎn)品質(zhì)量穩(wěn)定，實(shí)驗(yàn)效果明顯，貨期快，價(jià)格優(yōu)惠，歡迎垂詢訂購(gòu)！我公司長(zhǎng)期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗(yàn)所需全部相關(guān)試劑、熒光標(biāo)記抗體、單克隆抗體、多克隆抗體、各種標(biāo)記的二抗IgG/IgM/IgD/IgA等科研實(shí)驗(yàn)抗體。Anti-phospho-CBL2 (Tyr731)抗體用于**組化實(shí)驗(yàn),WB實(shí)驗(yàn),相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,FITC標(biāo)記,BIO等。
詳情介紹：
Rabbit Anti-phospho-CBL2 (Tyr731)
Cat. Number:
Anti-phospho-CBL2 (Tyr731)抗體KL-3089R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The proto oncogene c CBL was initially identified as the cellular homologue of v CBL oncogene that induces pre B cell lymphomas and myeloid leukemias in mice. In more recent studies CBL has been shown to be a negative regulator of tyrosine kinase signaling. The ubiquitin ligase activity of CBL leads to the degradation Anti-phospho-CBL2 (Tyr731)抗體of tyrosine kinases, thus attenuating the signal of receptors. Targets of CBL include activated protein tyrosine kinases belonging to the Src and Syk/Zap 70 families. An additional mechanism to attenuate receptor signaling is thought to be achieved by CBL’s interaction with downstream targets of tyrosine kinases, such as PI 3K and Vav.
Also known as:
phospho-C CBL (Tyr731); CBL2 (phospho-Tyr731); CBL2 (phospho-Tyr731); p-CBL2 (Tyr731); p-CBL2 (Y731); C CBL; Cas-Br-M (murine) ecotropic retroviral transforming sequence; Casitas B lineage lymphoma proto oncogene; CBL 2;E3 ubiquitin protein ligase CBL; Oncogene CBL2; Proto oncogene c CBL; RGD1561386;Anti-phospho-CBL2 (Tyr731)抗體 RING finger protein 55; RNF55v Signal transduction protein CBL; 4732447J05Rik; CBL_HUMAN.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, .
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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human CBL2 around the phosphorylation site of Tyr731.Anti-phospho-CBL2 (Tyr731)抗體
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Predicted Molecular Weight: 100kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions mustAnti-phospho-CBL2 (Tyr731)抗體 be determined by the end user.
Not yet tested in other applications.
Optimal working dilutions mustAnti-phospho-CBL2 (Tyr731)抗體 be determined by the end user.
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